妊娠滋养细胞疾病































妊娠滋养细胞疾病

Intermediate trophoblast 3 - low mag.jpg

显微镜下的中间型滋养细胞英语intermediate trophoblast蜕膜和葡萄胎
分类和外部资源
醫學專科
婦產科學肿瘤学
DiseasesDB
2602
MedlinePlus
001496
eMedicine
med/866
MeSH
D031901

[编辑此条目的维基数据]


妊娠滋养细胞疾病英语:Gestational trophoblastic disease, GTD),是一组和妊娠相关的肿瘤。此类肿瘤非常罕见,并且出现于子宫且有生长失控。这类产生疾病的生殖细胞称之为滋养细胞(英语:trophoblasts),产生于怀孕期间生成胎盘的组织。


妊娠滋养细胞疾病有不同类型的疾病。葡萄胎在通常情况是良性的,但是一些情况也会转化具备恶性特征,极少数情况会恶化为绒毛膜癌并迅速扩散[1][2]。这类疾病对化学疗法非常敏感,并且有非常好的预后。


妊娠滋养细胞疾病可能会刺激怀孕,因为子宫可能会包括异常的胎儿组织。这类组织的生长速度相当于正常妊娠,并且产生一类绒膜促性腺激素[3]。尽管妊娠滋养细胞疾病会直接影响育龄期妇女,但很少病发于绝经期妇女[4]



相关


  • 滋养层肿瘤英语Trophoblastic neoplasms


参考





  1. ^ Seckl MJ, Sebire NJ, Berkowitz RS. Gestational trophoblastic disease. Lancet. August 2010, 376 (9742): 717–29. PMID 20673583. doi:10.1016/S0140-6736(10)60280-2. 


  2. ^ Lurain JR. Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole. Am. J. Obstet. Gynecol. December 2010, 203 (6): 531–9. PMID 20728069. doi:10.1016/j.ajog.2010.06.073. 


  3. ^ Gestational trophoblastic disease: Epidemiology, clinical manifestations and diagnosis. Chiang JW, Berek JS. In: UpToDate [Textbook of Medicine]. Basow, DS (Ed). Massachusetts Medical Society, Waltham, Massachusetts, USA, and Wolters Kluwer Publishers, Amsterdam, The Netherlands. 2010.


  4. ^ Chittenden B, Ahamed E, Maheshwari A. Choriocarcinoma in a postmenopausal woman. Obstet Gynecol. August 2009, 114 (2 Pt 2): 462–5. PMID 19622962. doi:10.1097/AOG.0b013e3181aa97e7. 




外部链接



  • Molar Pregnancy


  • MyMolarPregnancy.com Information about molar pregnancy and choriocarcinoma.

  • Pathology of molar pregnancy

  • EVERYTHING ABOUT MOLA, is the second highest treatment center in the world

  • Clinically reviewed gestational trophoblastic tumour information for patients, from Cancer Research UK

  • Cancer.Net: Gestational Trophoblastic Tumor






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