妊娠滋养细胞疾病
妊娠滋养细胞疾病 | |
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显微镜下的中间型滋养细胞、蜕膜和葡萄胎 | |
分类和外部资源 | |
醫學專科 | 婦產科學、肿瘤学 |
DiseasesDB | 2602 |
MedlinePlus | 001496 |
eMedicine | med/866 |
MeSH | D031901 |
妊娠滋养细胞疾病(英语:Gestational trophoblastic disease, GTD),是一组和妊娠相关的肿瘤。此类肿瘤非常罕见,并且出现于子宫且有生长失控。这类产生疾病的生殖细胞称之为滋养细胞(英语:trophoblasts),产生于怀孕期间生成胎盘的组织。
妊娠滋养细胞疾病有不同类型的疾病。葡萄胎在通常情况是良性的,但是一些情况也会转化具备恶性特征,极少数情况会恶化为绒毛膜癌并迅速扩散[1][2]。这类疾病对化学疗法非常敏感,并且有非常好的预后。
妊娠滋养细胞疾病可能会刺激怀孕,因为子宫可能会包括异常的胎儿组织。这类组织的生长速度相当于正常妊娠,并且产生一类绒膜促性腺激素[3]。尽管妊娠滋养细胞疾病会直接影响育龄期妇女,但很少病发于绝经期妇女[4]。
相关
- 滋养层肿瘤
参考
^ Seckl MJ, Sebire NJ, Berkowitz RS. Gestational trophoblastic disease. Lancet. August 2010, 376 (9742): 717–29. PMID 20673583. doi:10.1016/S0140-6736(10)60280-2.
^ Lurain JR. Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole. Am. J. Obstet. Gynecol. December 2010, 203 (6): 531–9. PMID 20728069. doi:10.1016/j.ajog.2010.06.073.
^ Gestational trophoblastic disease: Epidemiology, clinical manifestations and diagnosis. Chiang JW, Berek JS. In: UpToDate [Textbook of Medicine]. Basow, DS (Ed). Massachusetts Medical Society, Waltham, Massachusetts, USA, and Wolters Kluwer Publishers, Amsterdam, The Netherlands. 2010.
^ Chittenden B, Ahamed E, Maheshwari A. Choriocarcinoma in a postmenopausal woman. Obstet Gynecol. August 2009, 114 (2 Pt 2): 462–5. PMID 19622962. doi:10.1097/AOG.0b013e3181aa97e7.
外部链接
- Molar Pregnancy
MyMolarPregnancy.com Information about molar pregnancy and choriocarcinoma.- Pathology of molar pregnancy
- EVERYTHING ABOUT MOLA, is the second highest treatment center in the world
- Clinically reviewed gestational trophoblastic tumour information for patients, from Cancer Research UK
- Cancer.Net: Gestational Trophoblastic Tumor
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