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Showing posts from March 12, 2019

Brain-derived neurotrophic factor

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BDNF Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1BND, 1B8M Identifiers Aliases BDNF , brain-derived neurotrophic factor, ANON2, BULN2, Brain-derived neurotrophic factor, brain derived neurotrophic factor External IDs OMIM: 113505 MGI: 88145 HomoloGene: 7245 GeneCards: BDNF Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p14.1 Start 27,654,893 bp [1] End 27,722,058 bp [1] Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2 E3|2 56.63 cM Start 109,674,700 bp [2] End 109,727,007 bp [2] RNA expression pattern More reference expression data Gene ontology Molecular function • receptor binding • neurotrophin TRKB receptor binding • growth factor activity • protein binding Cellular component • cytoplasm • perinuclear region of cytoplasm • mitochondrion • nuclear speck • cytoplasmic vesicle • extracellular region • extracellular space • synaptic ve